Nutritional Genomics

Genetics is an exciting and evolving field. In the past your genes were considered as unchanging as the color of your eyes or the shape of your face. Now we know we can alter the expression of your genes, moving you away from disease, despite a strong family tendency.

Now we know we can alter the expression of your genes, moving you away from disease, despite a strong family tendency.

Nutritional genomics can remove the fear factor surrounding a disease that exists in your family tree, and the anxiety of whether the same problem might befall you.

In other words, if most women in your family have thyroid disease, that doesn’t mean you have to develop it.

If most men in your family die young from heart disease, that doesn’t have to be you too.

Nutritional genomics opens the door to changing the very expression of your genes.

There’s much about our genetics that remains to be discovered, but with the knowledge currently to hand, there are incredible opportunities to positively influence your health.

Here at Root Cause we offer genetic panels that focus on your area of concern. There are many panel options, but it’s likely that only one or two are required for you, based on your health condition and that of your family.

Testing is easy; a quick swab of the inside of your mouth is all that’s required.

How does it work?

Your genes are tested for the presence of certain variations known as SNPs (single nucleotide polymorphism, called “snips”). We all have SNPs, it just depends on which ones and in which combination.

Here at Root Cause we only test for the SNPs for which we have nutritional options to improve their function. Fortunately, that list is expanding regularly, as we continue to learn more.

SNPs can affect your ability to absorb, metabolize or eliminate certain nutrients. It can affect their biological action too.

Imagine you were taking vitamin D3 religiously but when your doctor measures it in your blood it’s still very low. You’re taking it; why doesn’t it show an increase? You could have a SNP that impacts your ability to “activate” your vitamin D. The solution? Taking an active form, since your body is unable to do it itself. Having discovered the presence of this SNP and addressing it nutritionally, you can now receive all the wonderful benefits of vitamin D3.

Why do you get sicker than other people?

SNPs can also majorly impact your ability to recover. Let’s say you get a bad flu. Your spouse got it and he/she recovered after several days. You haven’t been the same since.

Why the difference? Your SNPs are different from those of your spouse. Do you have to remain feeling ill? Not at all, you just need the correct targeted nutrition to support your genetics

The goal of nutritional genomics is to optimize your nutrition, your ability to heal, and your
ability to repair, all based on your genotype, which is your specific genetic make-up.

The beautiful part is that once you remove the stress off your body by doing the tailor-made programs we offer, you may not need continued nutritional support. Unburdening your system is sometimes all that’s required once the personalized nutrition has re-set your genetics.

What is your risk for disease?

The presence of certain SNPs and their subsequent effect on your body can predict your risk for developing specific conditions or diseases.

This isn’t bad news; it’s just the reality of your genetics. It doesn’t mean you have to get ill; you just need to adjust your nutrition, diet and lifestyle in a certain specific fashion.

Is it difficult? Not at all.

Rather, it’s exciting to know that you’re steering yourself away from diseases and conditions that can affect your ability to live your life to the fullest.

Targeted and individualized treatment alters the expression of your genes, thereby lowering your risk of developing a condition, or improving your chance of recovery if you already have it.

If you’ve had your genes since the day you were born, why do they suddenly “act up” and make you sick? Very good question.

Your SNPs create a genetic predisposition, but it’s just that a “leaning towards”. The trouble arises when life brings “triggering events” to you. Such events include infections, surgery, pregnancy, environmental toxins, poor diet, allergies, trauma, and emotional stress.

Any one of these events can be enough to push a SNP over the edge and begin you down the road of ill health. A poor health condition or disease continues unresolved because you’re unable to fully handle the metabolic deficiency or inflammatory state created.

Targeted nutrition for your SNPs resolves the issue, moving you back towards regained health.

Available Panels

Methylation – is used in over 250 biochemical processes in the body, and when compromised it can affect the following:

  1. Neurotransmitter production, which impacts memory, focus, concentration, sleep, lowers pain threshold and seizure threshold, emotional instability, tremors or poor fine motor skills.
  2. Cell turnover and repair
  3. Membrane function
  4. Energy (mitochondrial) function, which can involve a poor ability to clear toxins Your mitochondria are little energy factories found inside every cell.

Of course, every cell requires energy but the systems with the highest requirements are the nervous system and immune system. Mitochondrial weakness is more common than previously thought and includes such problems as:

  • Chronic fatigue
  • Exercise intolerance
  • Low muscle tone
  • Mental fatigue
  • Cognitive decline
  • Immune function, causing weakness of your immune system
  • Poor neurological healing

This panel evaluates any tendency towards cellular inflammation, autophagy (an internal recycling system that maintains cell health and prevents growth of malicious cells), a greater impact from environmental inflammation, and skin and joint conditions.

Common conditions associated with the need for this panel include:

  • Asthma
  • Chronic infections
  • Eczema/Psoriasis
  • Hashimoto’s
  • Rheumatoid Arthritis
  • Lupus
  • Sjogren’s
  • Chronic dry eyes
  • Any autoimmune disease
  • Inflammatory bowel disease
  • Chronic fatigue
  • Immune weakness

This panel measures genes that manufacture neurotransmitters, affecting your mood and behavior, along with inflammation and autophagy.

Common conditions associated with the need for this panel include:

  • Adult ADD / ADHD
  • Headaches / Migraine / Cluster
  • Seizure Disorders
  • Post Concussion Syndrome
  • Tics / Tourette’s
  • Vertigo / Dizziness
  • Anxiety Disorder / Depression / Major Affective Disorder
  • Bi-polar
  • Alzheimer’s / Dementia / Memory Loss
  • Schizophrenia / Psychosis
  • Macular Degeneration
  • ALS
  • Parkinson’s / Gait Disorders
  • Neuropathies / Neuralgias

Neurotransmitters, when functioning normally, allow you to enjoy low anxiety and a low risk of depression. You are calm, relaxed, sleep well, and have a low pain and seizure risk.

There are “warrior genes” and “depression genes”. With the depression gene people are less able to recover (“more refractory”) from anxiety and depression.

There’s a SNP that controls GABA production, a neurotransmitter, decreasing it. This leads to:

  • Dysphoria – a state of feeling unhappy, uneasy or dissatisfied
  • Anxiety
  • “Glass half empty” syndrome
  • Increased pain sensitivity
  • Sleep disorders
  • Spasticity
  • Low libido

This panel evaluates hormonal, metabolic and vitamin abnormalities in women that can produce undesirable effects such as weight gain, mood disturbances, insomnia, infertility, and fatigue.

In some instances, hormonal issues with estrogen and progesterone balance, or altered estrogen metabolism, can lead to an increased risk of blood clots, fluid imbalance, and increased risk of hypertension. In more severe cases, there can be an increased risk of cancer, miscarriage, placental separation and preeclampsia.

Women with the following symptoms in themselves or in their family should be evaluated:

  • Irregular Menstrual Cycles
  • Weight Gain
  • History of Cystic Ovaries (PCOS)
  • Decreased Fertility
  • Hair Loss
  • Recurring pre-menstrual breast tenderness
  • History of Miscarriage
  • Fibrocystic Breast
  • Excess facial or body hair
  • Post-Menopausal Hormone Replacement
  • Family History of Infertility or Miscarriage
  • Family history of Breast / Ovarian or Endometrial Cancer
  • Family History of Hypothyroidism
  • Family History of Obesity
  • Family History of Diabetes or Gestational Diabetes
  • Family History of Pre-eclampsia

This panel looks at autophagy, your ability to effectively “recycle” and maintain the

health of your cells. Optimum autophagy also prevents the growth of malicious cells.

Efficient autophagy is an anti-aging mechanism. On the other hand, poor autophagy can move you towards such diseases as:

  • Alzheimer’s
  • Dementia
  • Parkinson’s
  • MS
  • IBD
  • Type 2 diabetes
  • Macular degeneration
  • Autoimmune disease: Lupus, Sjogren’s RA
  • Most cancers
  • Autism or developmental delays

Detoxification enzymes are responsible for clearing environmental chemicals and by-products of detoxification from your body. Accumulation of these chemicals and by-products can create significant damage.

Having certain detoxification SNPs can decrease your quality of life as well as your life-span.

Imagine you’re going to be taking a particular drug. It would be good to know that certain SNPs lead to adverse drug reactions due to an inability to metabolize or break down the drug.

The problem is well known. Currently more than 130 commonly prescribed medications have labels that include known genetic related warnings and precautions.

Knowing you have such a SNP would result in the knowledge that you require a lowered drug dose, thereby preventing the drug from accumulating in your body and you becoming toxic.

Even commonly used antibiotics, such as Cipro, when a certain SNPs is present, can result in your feeling awful when taking it.

Such SNPs can influence your reaction to natural products as well. You know how “everyone” needs curcumin (turmeric)? It is beneficial, but not if you have a SNP that can induce hypertension (high blood pressure) when you take it.

Contact us to discuss with a doctor which panel
makes the most sense for you.

Should you learn more about your genetics?

If you have a strong genetic predisposition in your family towards a particular disease, yes.

If you’re not enjoying good health that’s another very good reason to explore how your genetics may be affecting you.

Finally, if you are at all worried about developing a certain condition or disease and want to know what your genetic risk is, evaluating your genetics can put you at ease and back in the driver’s seat. With this valuable knowledge and nutritional support you can direct your health where you want it to go.

Contact us if you have further questions or you want to discuss with a doctor which panel makes the most sense for you.

Contact us! 

Phone: 408-733-0400

Address: 20398 Blauer Dr. Saratoga, CA 95070

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